Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0657Predicted coding region AF_0657; Hypothetical protein; identified by GeneMark; putative. (145 aa)    
Predicted Functional Partners:
AF_0658
Conserved hypothetical protein; Similar to GB:L77117 PID:1591923 percent identity: 24.75; identified by sequence similarity; putative.
       0.773
AF_0659
Type II secretion system protein (gspE-2); Similar to GB:L77117 SP:Q58310 PID:1591575 percent identity: 38.17; identified by sequence similarity; putative.
       0.773
AF_0660
Conserved hypothetical protein; Similar to SP:P42979 PID:755602 PID:1146233 GB:AL009126 percent identity: 45.10; identified by sequence similarity; putative.
       0.631
AF_0661
Heterodisulfide reductase, subunit E, putative; Similar to GP:1890197 percent identity: 25.35; identified by sequence similarity; putative.
       0.631
AF_0662
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
       0.631
AF_0663
Heterodisulfide reductase, subunit A (hdrA-1); Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
       0.631
AF_2424
Conserved hypothetical protein; Similar to PID:1652337 percent identity: 27.67; identified by sequence similarity; putative.
  
    0.539
AF_2425
Methanol dehydrogenase regulatory protein (moxR); Similar to PID:1001216 PID:1001272 percent identity: 48.33; identified by sequence similarity; putative.
       0.516
AF_0664
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58031 PID:1591324 percent identity: 31.58; identified by sequence similarity; putative.
       0.443
AF_0665
O-sialoglycoprotein endopeptidase, putative; Could be involved in the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine; Belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
       0.404
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (10%) [HD]