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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0660Conserved hypothetical protein; Similar to SP:P42979 PID:755602 PID:1146233 GB:AL009126 percent identity: 45.10; identified by sequence similarity; putative. (91 aa)    
Predicted Functional Partners:
AF_0661
Heterodisulfide reductase, subunit E, putative; Similar to GP:1890197 percent identity: 25.35; identified by sequence similarity; putative.
       0.773
AF_0662
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
       0.773
AF_0663
Heterodisulfide reductase, subunit A (hdrA-1); Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
       0.773
AF_0657
Predicted coding region AF_0657; Hypothetical protein; identified by GeneMark; putative.
       0.631
AF_0658
Conserved hypothetical protein; Similar to GB:L77117 PID:1591923 percent identity: 24.75; identified by sequence similarity; putative.
       0.631
AF_0659
Type II secretion system protein (gspE-2); Similar to GB:L77117 SP:Q58310 PID:1591575 percent identity: 38.17; identified by sequence similarity; putative.
       0.631
dacZ
Conserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
     0.549
AF_0664
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58031 PID:1591324 percent identity: 31.58; identified by sequence similarity; putative.
       0.531
AF_0504
Conserved hypothetical protein; Similar to GB:L77117 PID:1500528 percent identity: 43.59; identified by sequence similarity; putative; Belongs to the UPF0282 family.
  
     0.494
AF_0665
O-sialoglycoprotein endopeptidase, putative; Could be involved in the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine; Belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
       0.481
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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