Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0665O-sialoglycoprotein endopeptidase, putative; Could be involved in the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine; Belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily. (195 aa)    
Predicted Functional Partners:
kae1
O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
   
 0.985
AF_0519
Predicted coding region AF_0519; Hypothetical protein; identified by GeneMark; putative.
    
 
 0.884
rps24e
SSU ribosomal protein S24E (rps24E); Similar to GB:L77117 SP:P54032 PID:1591099 percent identity: 40.20; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS24 family.
  
    0.806
AF_1117
DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative.
 
     0.791
spt4
DNA-directed RNA polymerase, subunit E'' (rpoE2); Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
 
     0.760
rps27ae
SSU ribosomal protein S27AE (rps27AE); Similar to GB:L77117 SP:P54031 PID:1591098 percent identity: 60.00; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.727
AF_1115
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
       0.727
infB
Translation initiation factor IF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
 
  
 0.715
rps15
SSU ribosomal protein S15P (rps15P); Similar to GB:L77117 SP:P54012 PID:1590839 percent identity: 62.00; identified by sequence similarity; putative.
 
   
 0.699
AF_0664
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58031 PID:1591324 percent identity: 31.58; identified by sequence similarity; putative.
       0.693
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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