Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_06752-hydroxy-6-oxohepta-2,4-dienoate hydrolase (todF); Similar to GB:M64080 SP:P23133 GB:U18304 PID:151222 percent identity: 26.35; identified by sequence similarity; putative. (238 aa)    
Predicted Functional Partners:
AF_0674
Conserved hypothetical protein; Similar to SP:Q12499 PID:1420682 PID:940841 percent identity: 34.19; identified by sequence similarity; putative.
       0.776
AF_0671
acyl-CoA dehydrogenase (acd-4); Similar to SP:P45867 PID:853760 GB:AL009126 percent identity: 37.93; identified by sequence similarity; putative.
    
 0.656
AF_0673
Mercuric resistance operon regulatory protein (merR); Similar to SP:P22853 PID:1129093 percent identity: 33.04; identified by sequence similarity; putative.
  
  
 0.590
AF_0364
ATP-dependent protease La (lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity).
 
  
 0.560
AF_1537
Carboxylesterase (est-2); Similar to GB:D14529 PID:402521 percent identity: 29.02; identified by sequence similarity; putative.
 
 
 0.556
AF_0865
Carboxylesterase (est-1); Similar to GB:D14529 PID:402521 percent identity: 27.06; identified by sequence similarity; putative.
  
 
 0.499
AF_1706
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase (pcbD); Similar to GP:1395174 percent identity: 29.41; identified by sequence similarity; putative.
  
 
 0.499
AF_1763
Lipase, putative; Similar to GB:M74010 SP:P37957 PID:143154 PID:2415721 GB:AL009126 percent identity: 33.54; identified by sequence similarity; putative.
  
 
 0.499
AF_2336
Carboxylesterase (est-3); Similar to GB:D14529 PID:402521 percent identity: 28.84; identified by sequence similarity; putative.
  
 
 0.499
icd
Isocitrate dehydrogenase, NADP (icd); Similar to GB:J02799 SP:P08200 PID:146432 GB:U00096 PID:1651560 percent identity: 57.18; identified by sequence similarity; putative; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
 
  
  0.495
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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