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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0690Predicted coding region AF_0690; Hypothetical protein; identified by GeneMark; putative. (252 aa)    
Predicted Functional Partners:
AF_2350
ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative.
   
 0.858
rpl40e
LSU ribosomal protein L40E (rpl40E); Similar to GB:L77117 SP:P54058 PID:1591423 percent identity: 73.33; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
    
  0.761
cobB2
Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
   
 
 0.694
cobB1
Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
   
 
 0.694
smc
Chromosome segregation protein (smc1); Required for chromosome condensation and partitioning. Belongs to the SMC family.
   
 0.609
AF_0691
Predicted coding region AF_0691; Hypothetical protein; identified by GeneMark; putative.
       0.584
serA
Phosphoglycerate dehydrogenase (serA); Similar to GB:L77117 PID:1591676 percent identity: 48.77; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.581
AF_1813
TBP-interacting protein TIP49; Similar to GP:2225877 percent identity: 47.43; identified by sequence similarity; putative.
    
 0.564
AF_0692
Conserved hypothetical protein; Similar to GP:1065485 percent identity: 29.17; identified by sequence similarity; putative.
       0.561
AF_0477
AAA superfamily ATPase; Similar to GB:D78275 SP:Q92524 PID:1526426 PID:2213932 percent identity: 34.97; identified by sequence similarity; putative; Belongs to the AAA ATPase family.
   
 0.546
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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