Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0705Conserved hypothetical protein; Similar to GB:L77117 PID:1591957 percent identity: 38.07; identified by sequence similarity; putative; Belongs to the peptidase S16 family. (590 aa)    
Predicted Functional Partners:
AF_0704
Conserved hypothetical protein; Similar to PID:1499713 GB:L77117 PID:1499713 percent identity: 35.36; identified by sequence similarity; putative.
       0.625
AF_2308
Arsenite transport protein (arsB); Similar to SP:P08691 GB:J02591 SP:P37310 GB:X80057 PID:151858 percent identity: 24.66; identified by sequence similarity; putative.
       0.608
AF_0700
Aspartate kinase (lysC); Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 49.13; identified by sequence similarity; putative; Belongs to the aspartokinase family.
 
     0.477
AF_0701
Predicted coding region AF_0701; Hypothetical protein; identified by GeneMark; putative.
       0.464
thi4
Thiamine biosynthetic enzyme (thi1); Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
       0.464
AF_0703
Predicted coding region AF_0703; Hypothetical protein; identified by GeneMark; putative.
       0.464
AF_1251
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57570 PID:1590883 percent identity: 38.16; identified by sequence similarity; putative.
  
     0.427
AF_0698
Predicted coding region AF_0698; Hypothetical protein; identified by GeneMark; putative.
  
    0.424
AF_1810
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57567 PID:1498868 percent identity: 43.77; identified by sequence similarity; putative.
  
     0.408
AF_0462
Conserved hypothetical transmembrane protein; Similar to GB:L77117 SP:Q57882 PID:1591144 percent identity: 33.08; identified by sequence similarity; putative.
  
     0.402
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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