Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppsAPhosphoenolpyruvate synthase (ppsA); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (753 aa)    
Predicted Functional Partners:
eno
Enolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.970
AF_1252
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:L77117 PID:1591862 percent identity: 63.26; identified by sequence similarity; putative.
   
 
 0.950
AF_0749
2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA); Similar to GP:1565183 percent identity: 33.70; identified by sequence similarity; putative.
    
 0.945
AF_1727
Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative.
    
 0.943
ppcA
Predicted coding region AF_1486; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
     
 0.941
AF_1699
Pyruvate ferredoxin oxidoreductase, subunit gamma (porG); Similar to PID:1197358 percent identity: 50.84; identified by sequence similarity; putative.
  
 
 0.918
AF_2055
2-ketoisovalerate ferredoxin oxidoreductase, subunit gamma (vorG); Similar to PID:1197358 percent identity: 45.21; identified by sequence similarity; putative.
  
 
 0.917
AF_1700
Pyruvate ferredoxin oxidoreductase, subunit delta (porD); Similar to PID:1197359 percent identity: 53.12; identified by sequence similarity; putative.
    
 0.914
AF_2054
2-ketoisovalerate ferredoxin oxidoreductase, subunit delta (vorD); Similar to PID:1197359 percent identity: 51.52; identified by sequence similarity; putative.
    
 0.914
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
  0.913
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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