Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0717Conserved hypothetical protein; Similar to GB:D37799 SP:P39760 PID:520844 PID:1377829 GB:AL009126 percent identity: 23.89; identified by sequence similarity; putative. (214 aa)    
Predicted Functional Partners:
AF_0715
Potassium channel, putative; Similar to GB:L02750 SP:Q09470 PID:186663 percent identity: 39.53; identified by sequence similarity; putative.
 
     0.802
AF_0716
Conserved hypothetical protein; Similar to PID:1001350 PID:1001359 percent identity: 28.12; identified by sequence similarity; putative.
       0.781
AF_0718
Predicted coding region AF_0718; Hypothetical protein; identified by GeneMark; putative.
       0.693
mtd
N5,N10-methylenetetrahydromethanopterin dehydrogenase (mtd); Catalyzes the oxidation of methylene-H(4)MPT to methenyl- H(4)MPT(+); Belongs to the MTD family.
       0.614
AF_0719
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57890 PID:1591152 percent identity: 30.97; identified by sequence similarity; putative.
       0.499
AF_0722
Cobalamin biosynthesis precorrin-6Y methylase (cbiE); Similar to GB:L77117 PID:1592152 percent identity: 32.40; identified by sequence similarity; putative.
  
    0.442
AF_1673
Potassium channel, putative; Similar to PID:1652235 percent identity: 36.27; identified by sequence similarity; putative.
  
     0.433
AF_0995
Conserved hypothetical protein; Similar to GB:L77117 PID:1591923 percent identity: 26.90; identified by sequence similarity; putative.
  
     0.411
AF_0713
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA-1); Similar to GB:L77117 SP:Q58114 PID:1591418 percent identity: 37.50; identified by sequence similarity; putative; Belongs to the HisA/HisF family.
       0.400
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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