Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cbiNCobalt transport protein (cbiN); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (87 aa)    
Predicted Functional Partners:
cbiM
Cobalamin biosynthesis protein (cbiM-1); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
 
 
 0.999
AF_0730
Cobalt transport protein (cbiQ-1); Similar to GP:1419077 percent identity: 32.61; identified by sequence similarity; putative.
 
 
 0.998
cbiHC
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate; In the C-terminal section; belongs to the CobH family.
 
  
 0.994
AF_0731
Cobalt transport ATP-binding protein (cbiO-1); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
 0.994
AF_1843
Cobalamin biosynthesis protein (cbiM-2); May be involved in nickel transport; Belongs to the CbiM family. NikM subfamily.
 
 
 0.954
AF_1842
Cobalt transport protein (cbiQ-2); Similar to GB:L77117 PID:1592192 percent identity: 30.34; identified by sequence similarity; putative.
  
 
 0.923
AF_1841
Cobalt transport ATP-binding protein (cbiO-2); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
  
 
 0.922
AF_0725
Cobalamin biosynthesis precorrin methylase (cbiG); Similar to PID:1651952 percent identity: 30.69; identified by sequence similarity; putative.
 
  
 0.910
AF_0727
Cobalamin biosynthesis precorrin-2 methyltransferase (cbiL); Similar to PID:1652770 percent identity: 31.46; identified by sequence similarity; putative; Belongs to the precorrin methyltransferase family.
 
  
 0.904
cbiT
Cobalamin biosynthesis precorrin-8W decarboxylase (cbiT); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
   
 0.901
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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