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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0731Cobalt transport ATP-binding protein (cbiO-1); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity). (326 aa)    
Predicted Functional Partners:
AF_0730
Cobalt transport protein (cbiQ-1); Similar to GP:1419077 percent identity: 32.61; identified by sequence similarity; putative.
 
 0.998
AF_1842
Cobalt transport protein (cbiQ-2); Similar to GB:L77117 PID:1592192 percent identity: 30.34; identified by sequence similarity; putative.
 
 0.991
cbiN
Cobalt transport protein (cbiN); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
 
 
 0.986
cbiM
Cobalamin biosynthesis protein (cbiM-1); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
 
 
 0.984
AF_1843
Cobalamin biosynthesis protein (cbiM-2); May be involved in nickel transport; Belongs to the CbiM family. NikM subfamily.
 
 0.984
cbiHC
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate; In the C-terminal section; belongs to the CobH family.
  
  
 0.949
AF_1171
Predicted coding region AF_1171; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.909
AF_1841
Cobalt transport ATP-binding protein (cbiO-2); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
  
  
 
0.909
AF_1169
Conserved hypothetical protein; Similar to GP:1674297 percent identity: 28.16; identified by sequence similarity; putative.
   
 
 0.864
cbiT
Cobalamin biosynthesis precorrin-8W decarboxylase (cbiT); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
  
 0.849
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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