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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0735Conserved hypothetical protein; Similar to GB:L77117 SP:Q58387 PID:1591640 percent identity: 36.87; identified by sequence similarity; putative. (457 aa)    
Predicted Functional Partners:
AF_0075
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58387 PID:1591640 percent identity: 30.21; identified by sequence similarity; putative.
  
  
 
0.917
polB
Conserved hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family.
  
 
 
 0.899
AF_1332
Predicted coding region AF_1332; Hypothetical protein; identified by GeneMark; putative.
   
 
 0.791
topA
DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...]
 
 
 
 0.692
AF_1530
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60351 PID:1590840 percent identity: 45.28; identified by sequence similarity; putative.
  
     0.662
AF_2325
Predicted coding region AF_2325; Hypothetical protein; identified by GeneMark; putative.
 
     0.658
endA
tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
     0.656
polC
Conserved hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
 
     0.645
AF_0525
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58607 PID:1591839 percent identity: 46.86; identified by sequence similarity; putative.
  
     0.628
AF_2154
Conserved hypothetical protein; Similar to GB:L77117 PID:1500525 percent identity: 40.14; identified by sequence similarity; putative; Belongs to the UPF0179 family.
  
     0.628
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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