Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0737Predicted coding region AF_0737; Hypothetical protein; identified by GeneMark; putative. (67 aa)    
Predicted Functional Partners:
thiC
Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.916
thiE
Thiamine phosphate pyrophosphorylase (thiE); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.904
AF_2208
Hydroxymethylpyrimidine phosphate kinase (thiD); Similar to GP:1842118 percent identity: 35.47; identified by sequence similarity; putative.
  
  
 0.886
AF_2198
Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative.
  
 
 0.837
AF_0531
Molybdenum cofactor biosynthesis protein (moeB); Similar to PID:1653525 percent identity: 43.96; identified by sequence similarity; putative.
  
 
 0.830
AF_0553
Thiamine biosynthesis protein (thiF); Similar to SP:P30138 PID:396331 PID:414234 GB:U00096 PID:1790425 percent identity: 38.75; identified by sequence similarity; putative.
  
 
 0.830
AF_1441
Predicted coding region AF_1441; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.830
AF_0274
Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.
  
  
 0.645
thiM
Hydroxyethylthiazole kinase (thiM); Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
    0.612
AF_0388
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58826 PID:1500312 percent identity: 40.13; identified by sequence similarity; putative.
  
  
 0.605
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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