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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0737Predicted coding region AF_0737; Hypothetical protein; identified by GeneMark; putative. (67 aa)    
Predicted Functional Partners:
thiE
Thiamine phosphate pyrophosphorylase (thiE); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.948
thiC
Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.947
AF_2208
Hydroxymethylpyrimidine phosphate kinase (thiD); Similar to GP:1842118 percent identity: 35.47; identified by sequence similarity; putative.
  
    0.921
AF_0531
Molybdenum cofactor biosynthesis protein (moeB); Similar to PID:1653525 percent identity: 43.96; identified by sequence similarity; putative.
  
 
 0.920
AF_0553
Thiamine biosynthesis protein (thiF); Similar to SP:P30138 PID:396331 PID:414234 GB:U00096 PID:1790425 percent identity: 38.75; identified by sequence similarity; putative.
  
 
 0.920
AF_1441
Predicted coding region AF_1441; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.920
AF_2198
Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative.
  
 
 0.890
AF_1321
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58873 PID:1592117 percent identity: 40.07; identified by sequence similarity; putative.
  
 
 0.801
AF_1595
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58558 PID:1592323 percent identity: 35.88; identified by sequence similarity; putative.
  
 
 0.801
AF_1039
Conserved hypothetical protein; Similar to GB:M20144 SP:P40403 PID:289302 GB:AL009126 percent identity: 26.56; identified by sequence similarity; putative.
    
   0.735
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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