STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dapFDiaminopimelate epimerase (dapF); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (280 aa)    
Predicted Functional Partners:
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 0.998
dapB
Dihydrodipicolinate reductase (dapB); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
   
 0.987
dapA
Dihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.987
AF_0409
Aspartate aminotransferase (aspB-4); Similar to PID:1001492 PID:1001578 percent identity: 45.24; identified by sequence similarity; putative.
  
 
 0.973
AF_0051
Succinyl-diaminopimelate desuccinylase (dapE-1); Similar to GB:L77117 SP:Q57899 PID:1591159 percent identity: 30.52; identified by sequence similarity; putative.
 
  
 0.930
carB
Carbamoyl-phosphate synthase, large (or ammonia) subunit (carB); Similar to PID:1001613 PID:1001668 percent identity: 65.08; identified by sequence similarity; putative.
    
 0.924
AF_0904
Succinyl-diaminopimelate desuccinylase (dapE-2); Similar to GB:L77117 SP:Q57899 PID:1591159 percent identity: 43.77; identified by sequence similarity; putative.
    
 0.920
AF_0746
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57608 PID:1590906 percent identity: 32.75; identified by sequence similarity; putative.
 
    0.859
AF_2200
Mutator protein MutT, putative; Similar to GB:L77117 PID:1500003 percent identity: 41.98; identified by sequence similarity; putative.
  
 
 0.795
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
  
 0.790
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.