Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0751Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (168 aa)    
Predicted Functional Partners:
AF_1224
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58188 PID:1499598 percent identity: 47.18; identified by sequence similarity; putative.
     0.969
AF_0750
2-oxoacid ferredoxin oxidoreductase, subunit beta (orB); Similar to GP:1565184 percent identity: 49.21; identified by sequence similarity; putative.
  
    0.781
AF_0749
2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA); Similar to GP:1565183 percent identity: 33.70; identified by sequence similarity; putative.
       0.773
AF_0708
Conserved hypothetical protein; Similar to percent identity: 38.78; identified by sequence similarity; putative.
 
     0.768
AF_0748
Predicted coding region AF_0748; Hypothetical protein; identified by GeneMark; putative.
       0.757
nac
Conserved hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.698
tfe
Transcription initiation factor IIE, subunit alpha, putative; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and dest [...]
 
     0.693
pfdB
erpK protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
  
     0.676
AF_0361
UDP-glucose 4-epimerase (galE-1); Similar to GB:L77117 SP:Q57664 PID:1590951 percent identity: 38.64; identified by sequence similarity; putative.
 
     0.672
AF_0421
Predicted coding region AF_0421; Hypothetical protein; identified by GeneMark; putative.
       0.624
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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