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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0792Predicted coding region AF_0792; Hypothetical protein; identified by GeneMark; putative. (256 aa)    
Predicted Functional Partners:
AF_0793
Conserved hypothetical transmembrane protein; Similar to GB:L77117 SP:Q58204 PID:1592308 percent identity: 32.06; identified by sequence similarity; putative.
       0.570
AF_0504
Conserved hypothetical protein; Similar to GB:L77117 PID:1500528 percent identity: 43.59; identified by sequence similarity; putative; Belongs to the UPF0282 family.
 
     0.555
AF_0876
5'-nucleotidase (nt5); Similar to GB:X55740 SP:P21589 PID:1143806 PID:23897 percent identity: 30.87; identified by sequence similarity; putative.
  
    0.471
AF_0821
Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative.
 
     0.463
AF_0814
Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
 
     0.455
rad50
Purine NTPase, putative; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
 
     0.431
AF_1496
Predicted coding region AF_1496; Hypothetical protein; identified by GeneMark; putative.
  
     0.430
rgy
Reverse gyrase (top-RG); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
  
     0.425
AF_0521
Protease synthase and sporulation regulator Pai1, putative; Similar to GB:L77117 PID:1591837 percent identity: 52.41; identified by sequence similarity; putative; Belongs to the acetyltransferase family.
 
     0.401
AF_0820
Predicted coding region AF_0820; Hypothetical protein; identified by GeneMark; putative.
 
     0.400
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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