Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lysADiaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (419 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase (dapF); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
 
 0.998
dapA
Dihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.996
dapB
Dihydrodipicolinate reductase (dapB); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
   
 0.988
AF_0700
Aspartate kinase (lysC); Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 49.13; identified by sequence similarity; putative; Belongs to the aspartokinase family.
  
 0.960
AF_0409
Aspartate aminotransferase (aspB-4); Similar to PID:1001492 PID:1001578 percent identity: 45.24; identified by sequence similarity; putative.
  
  
 0.938
AF_1422
Aspartate racemase; Similar to GP:1545809 percent identity: 28.02; identified by sequence similarity; putative.
    
  0.906
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.816
AF_0935
Homoserine dehydrogenase (hom); Similar to GB:L77117 PID:1500499 percent identity: 47.85; identified by sequence similarity; putative.
  
 0.814
AF_0799
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58040 PID:1591334 percent identity: 42.96; identified by sequence similarity; putative.
       0.790
AF_0866
Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
   
 0.755
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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