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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0820Predicted coding region AF_0820; Hypothetical protein; identified by GeneMark; putative. (94 aa)    
Predicted Functional Partners:
hisF
Imidazoleglycerol-phosphate synthase, cyclase subunit (hisF); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
       0.847
AF_0821
Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative.
       0.813
acyP
Acylphosphatase (acyP); Similar to SP:P14620 percent identity: 36.76; identified by sequence similarity; putative.
       0.780
dacZ
Conserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
     0.569
AF_0817
Conserved hypothetical protein; Similar to GB:L77117 PID:1500447 percent identity: 42.53; identified by sequence similarity; putative.
       0.544
AF_0504
Conserved hypothetical protein; Similar to GB:L77117 PID:1500528 percent identity: 43.59; identified by sequence similarity; putative; Belongs to the UPF0282 family.
  
     0.435
dapB
Dihydrodipicolinate reductase (dapB); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
  
    0.416
AF_0792
Predicted coding region AF_0792; Hypothetical protein; identified by GeneMark; putative.
 
     0.400
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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