Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0865Carboxylesterase (est-1); Similar to GB:D14529 PID:402521 percent identity: 27.06; identified by sequence similarity; putative. (266 aa)    
Predicted Functional Partners:
rtcB
Conserved hypothetical protein; GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends; Belongs to the RtcB family.
       0.773
AF_0863
Predicted coding region AF_0863; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_0864
Predicted coding region AF_0864; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_0868
Alkyldihydroxyacetonephosphate synthase; Similar to GP:1808596 percent identity: 33.55; identified by sequence similarity; putative.
 
   
 0.688
gpsA
Glycerol-3-phosphate dehydrogenase (NAD(P)+) (gpsA); Similar to SP:P46919 PID:974332 PID:1146220 GB:AL009126 percent identity: 36.31; identified by sequence similarity; putative.
 
   
 0.659
AF_0866
Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
  
  
 0.656
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
 
 0.640
AF_0869
Conserved hypothetical protein; Similar to GP:1402531 percent identity: 48.31; identified by sequence similarity; putative; Belongs to the UPF0145 family.
       0.628
AF_1388
DNA helicase, putative; Similar to GB:L77117 SP:Q57568 PID:1590880 percent identity: 46.83; identified by sequence similarity; putative.
   
 0.617
AF_1822
Serine/threonine phosphatase (ppa); Similar to PID:1016001 percent identity: 31.94; identified by sequence similarity; putative.
   
 0.617
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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