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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mptEConserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (197 aa)    
Predicted Functional Partners:
AF_2043
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57851 PID:1591114 percent identity: 31.71; identified by sequence similarity; putative.
    
 0.942
AF_0719
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57890 PID:1591152 percent identity: 30.97; identified by sequence similarity; putative.
    
  0.903
AF_2383
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57890 PID:1591152 percent identity: 34.08; identified by sequence similarity; putative.
    
  0.903
thiI
Conserved hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.746
AF_2058
Conserved hypothetical protein; Similar to GB:L77117 PID:1499875 percent identity: 31.73; identified by sequence similarity; putative.
 
     0.674
AF_1775
Atrazine chlorohydrolase, putative; Similar to GB:L77117 SP:Q58110 PID:1591414 percent identity: 34.39; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
     0.634
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
 
   
 0.615
AF_1115
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
     0.613
priL
Conserved hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
 
     0.611
AF_0587
Conserved hypothetical protein; Similar to GB:L77117 PID:1499864 percent identity: 31.13; identified by sequence similarity; putative.
  
     0.576
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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