Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mptEConserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (197 aa)    
Predicted Functional Partners:
AF_2043
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57851 PID:1591114 percent identity: 31.71; identified by sequence similarity; putative.
    
 0.959
AF_0719
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57890 PID:1591152 percent identity: 30.97; identified by sequence similarity; putative.
    
  0.904
AF_2383
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57890 PID:1591152 percent identity: 34.08; identified by sequence similarity; putative.
    
  0.903
AF_2058
Conserved hypothetical protein; Similar to GB:L77117 PID:1499875 percent identity: 31.73; identified by sequence similarity; putative.
 
     0.806
thiI
Conserved hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.746
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
 
   
 0.742
ileS
isoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
       0.701
AF_1775
Atrazine chlorohydrolase, putative; Similar to GB:L77117 SP:Q58110 PID:1591414 percent identity: 34.39; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
     0.634
AF_0243
Conserved hypothetical protein; Similar to GB:L77117 PID:1590999 percent identity: 45.88; identified by sequence similarity; putative.
 
     0.632
AF_1414
Dihydropteroate synthase; Similar to GB:L77117 SP:Q57571 PID:1590884 percent identity: 40.82; identified by sequence similarity; putative.
 
   
 0.624
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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