close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0880Rubredoxin (rd-1); Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. (53 aa)    
Predicted Functional Partners:
AF_0344
Desulfoferrodoxin, putative; Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
  
  
 0.847
AF_0833
Desulfoferrodoxin (dfx); Similar to GB:M81168 SP:P20418 GB:M28848 PID:145115 PID:758676 percent identity: 63.03; identified by sequence similarity; putative; Belongs to the desulfoferrodoxin family.
  
  
 0.835
AF_1381
F420-nonreducing hydrogenase (vhtG); Similar to PID:602582 percent identity: 46.11; identified by sequence similarity; putative.
  
 
 0.834
AF_1518
DNA/pantothenate metabolism flavoprotein, putative; Similar to GB:L77117 SP:Q58140 PID:1499547 percent identity: 51.40; identified by sequence similarity; putative.
     
 0.735
AF_0166
Ferredoxin (fdx-2); Similar to SP:P29604 percent identity: 49.15; identified by sequence similarity; putative.
  
  
 0.618
AF_0270
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.565
thiI
Conserved hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.557
AF_0404
4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
     
 0.546
AF_0834
Ferritin, putative; Similar to GB:L42023 SP:P43707 PID:1007431 PID:1221522 PID:1205619 percent identity: 39.75; identified by sequence similarity; putative.
  
  
 0.542
pyrK
Cytochrome-c3 hydrogenase, subunit gamma; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
      
 0.541
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (24%) [HD]