Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0886S-adenosylhomocysteinase hydrolase (ahcY-1); Similar to GB:L77117 PID:1592034 percent identity: 31.71; identified by sequence similarity; putative. (326 aa)    
Predicted Functional Partners:
AF_2112
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Similar to PID:1103707 SP:P55299 percent identity: 28.08; identified by sequence similarity; putative.
  
 
 0.965
ahcY
S-adenosylhomocysteinase hydrolase (ahcY-2); May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
  
 
0.920
mtaD1
N-ethylammeline chlorohydrolase (trzA-1); Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
  
 
 0.918
mtaD2
N-ethylammeline chlorohydrolase (trzA-2); Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
  
 
 0.918
AF_1185
Iron-sulfur cluster binding protein; Similar to GB:L77117 SP:Q57563 PID:1590877 percent identity: 36.67; identified by sequence similarity; putative.
     
  0.900
AF_1186
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57564 PID:1498865 percent identity: 56.43; identified by sequence similarity; putative.
     
  0.900
AF_0935
Homoserine dehydrogenase (hom); Similar to GB:L77117 PID:1500499 percent identity: 47.85; identified by sequence similarity; putative.
  
 
 0.843
AF_2198
Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative.
  
 
 0.668
AF_0885
4-hydroxyphenylacetate-3-hydroxylase (hpaA-2); Similar to PID:974146 percent identity: 26.01; identified by sequence similarity; putative.
       0.623
glyA
Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.
  
 
 0.596
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.