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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0886S-adenosylhomocysteinase hydrolase (ahcY-1); Similar to GB:L77117 PID:1592034 percent identity: 31.71; identified by sequence similarity; putative. (326 aa)    
Predicted Functional Partners:
AF_2112
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Similar to PID:1103707 SP:P55299 percent identity: 28.08; identified by sequence similarity; putative.
  
 
 0.971
ahcY
S-adenosylhomocysteinase hydrolase (ahcY-2); May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
  
 
0.920
AF_1185
Iron-sulfur cluster binding protein; Similar to GB:L77117 SP:Q57563 PID:1590877 percent identity: 36.67; identified by sequence similarity; putative.
     
  0.900
AF_1186
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57564 PID:1498865 percent identity: 56.43; identified by sequence similarity; putative.
     
  0.900
AF_0935
Homoserine dehydrogenase (hom); Similar to GB:L77117 PID:1500499 percent identity: 47.85; identified by sequence similarity; putative.
  
 
 0.837
fusA
Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...]
  
 
 0.657
AF_0885
4-hydroxyphenylacetate-3-hydroxylase (hpaA-2); Similar to PID:974146 percent identity: 26.01; identified by sequence similarity; putative.
       0.623
glyA
Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.
  
 
 0.583
AF_0890
Predicted coding region AF_0890; Hypothetical protein; identified by GeneMark; putative.
       0.545
AF_0887
Ribose ABC transporter, ATP-binding protein (rbsA-1); Similar to GB:L10328 SP:P04983 GB:M13169 PID:147513 PID:290599 percent identity: 33.27; identified by sequence similarity; putative.
       0.541
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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