Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0899Conserved hypothetical protein; Similar to GB:L77117 SP:Q58527 PID:1499979 percent identity: 45.15; identified by sequence similarity; putative. (274 aa)    
Predicted Functional Partners:
endA
tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
 
     0.796
AF_0901
Conserved hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
 
     0.750
AF_0902
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58096 PID:1591398 percent identity: 33.62; identified by sequence similarity; putative.
       0.704
AF_0904
Succinyl-diaminopimelate desuccinylase (dapE-2); Similar to GB:L77117 SP:Q57899 PID:1591159 percent identity: 43.77; identified by sequence similarity; putative.
 
     0.703
rpl40e
LSU ribosomal protein L40E (rpl40E); Similar to GB:L77117 SP:P54058 PID:1591423 percent identity: 73.33; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
 
     0.693
AF_1062
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57905 PID:1591185 percent identity: 57.76; identified by sequence similarity; putative.
 
     0.680
AF_1972
Conserved hypothetical protein; Similar to GB:L77117 PID:1500551 percent identity: 30.07; identified by sequence similarity; putative.
 
     0.673
AF_0587
Conserved hypothetical protein; Similar to GB:L77117 PID:1499864 percent identity: 31.13; identified by sequence similarity; putative.
  
     0.672
AF_0903
Predicted coding region AF_0903; Hypothetical protein; identified by GeneMark; putative.
       0.647
rpl44e
LSU ribosomal protein L44E (rpl44E); Binds to the 23S rRNA.
 
     0.642
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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