Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dapADihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (289 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase (dapB); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
 
 0.999
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.996
dapF
Diaminopimelate epimerase (dapF); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
 
  
 0.987
rps17e
SSU ribosomal protein S17E (rps17E); Similar to PIR:S63968 percent identity: 52.63; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS17 family.
  
    0.985
asd
Aspartate-semialdehyde dehydrogenase (asd); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.982
AF_0935
Homoserine dehydrogenase (hom); Similar to GB:L77117 PID:1500499 percent identity: 47.85; identified by sequence similarity; putative.
 
 
 0.949
gatC
Glu-tRNA amidotransferase, subunit C (gatC); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity); Belongs to the GatC family.
  
  
 0.915
AF_0700
Aspartate kinase (lysC); Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 49.13; identified by sequence similarity; putative; Belongs to the aspartokinase family.
 
  
 0.882
rps15
SSU ribosomal protein S15P (rps15P); Similar to GB:L77117 SP:P54012 PID:1590839 percent identity: 62.00; identified by sequence similarity; putative.
  
    0.829
AF_2068
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family.
 
    0.815
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (16%) [HD]