Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_0918Pyruvate formate-lyase activating enzyme (act-2); Similar to GB:L77117 SP:Q58214 PID:1499627 percent identity: 42.65; identified by sequence similarity; putative. (283 aa)    
Predicted Functional Partners:
glyS
glycyl-tRNA synthetase (glyS); Catalyzes the attachment of glycine to tRNA(Gly).
 
     0.799
cofD
Conserved hypothetical protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
  
    0.777
AF_0919
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58346 PID:1499771 percent identity: 40.97; identified by sequence similarity; putative.
 
     0.741
pyrC
Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
    0.678
AF_2226
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57864 PID:1591124 percent identity: 47.67; identified by sequence similarity; putative.
  
     0.631
AF_1064
ABC transporter, ATP-binding protein, putative; Similar to PID:1653298 percent identity: 36.02; identified by sequence similarity; putative.
 
  
 0.573
aspS
aspartyl-tRNA synthetase (aspS); Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
       0.569
AF_0915
Predicted coding region AF_0915; Hypothetical protein; identified by GeneMark; putative.
       0.558
AF_2078
Predicted coding region AF_2078; Hypothetical protein; identified by GeneMark; putative.
 
    0.546
AF_1768
Dipeptide ABC transporter, permease protein (dppB); Similar to SP:P37316 PID:349226 PID:466682 GB:U00096 PID:1789965 percent identity: 39.34; identified by sequence similarity; putative.
       0.541
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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