Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0925Predicted coding region AF_0925; Hypothetical protein; identified by GeneMark; putative. (315 aa)    
Predicted Functional Partners:
AF_0924
Predicted coding region AF_0924; Hypothetical protein; identified by GeneMark; putative.
       0.697
AF_0926
Conserved hypothetical protein; Similar to GB:M24143 SP:P15050 PID:450383 PID:522184 GB:U00096 percent identity: 36.11; identified by sequence similarity; putative.
       0.620
AF_0364
ATP-dependent protease La (lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity).
  
 
 0.518
AF_2034
X-pro aminopeptidase (pepQ); Similar to GB:L77117 SP:Q58216 PID:1591498 percent identity: 34.63; identified by sequence similarity; putative; Belongs to the peptidase M24B family.
  
  
 0.462
infB
Translation initiation factor IF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
  
  
 0.459
AF_1420
Membrane protein; Similar to GB:L77117 SP:Q58237 PID:1591514 percent identity: 51.83; identified by sequence similarity; putative.
  
 
 0.454
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.433
rlmE
Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
   
  
 0.424
AF_2387
Conserved hypothetical protein; Similar to SP:P54158 PID:1256620 GB:AL009126 percent identity: 23.42; identified by sequence similarity; putative.
   
 
 0.414
hmgA
3-hydroxy-3-methylglutaryl-coenzyme A reductase (mvaA); Converts HMG-CoA to mevalonate.
  
 
 0.404
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.