Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0927Conserved hypothetical protein; Similar to GB:L77117 SP:Q57662 PID:1498984 percent identity: 47.83; identified by sequence similarity; putative. (188 aa)    
Predicted Functional Partners:
AF_1646
Conserved hypothetical protein; Similar to GB:L77117 PID:1591632 percent identity: 34.23; identified by sequence similarity; putative.
 
  
 0.992
AF_1645
Pantothenate metabolism flavoprotein (dfp); Similar to GB:L77117 PID:1591587 percent identity: 42.42; identified by sequence similarity; putative.
 
  
 0.981
mfnA
Group II decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.925
AF_1395
Conserved hypothetical protein; Similar to GB:L77117 PID:1592047 percent identity: 45.41; identified by sequence similarity; putative; In the N-terminal section; belongs to the UPF0200 family.
 
     0.753
aspS
aspartyl-tRNA synthetase (aspS); Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
  
    0.642
AF_1695
Thiamine biosynthesis protein (apbA); Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
 
   
 0.609
hisD
Histidinol dehydrogenase (hisD); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.599
AF_1972
Conserved hypothetical protein; Similar to GB:L77117 PID:1500551 percent identity: 30.07; identified by sequence similarity; putative.
 
     0.598
AF_1115
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
    0.578
AF_0994
Conserved hypothetical protein; Similar to SP:P54168 PID:1256633 GB:AL009126 percent identity: 43.75; identified by sequence similarity; putative.
       0.569
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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