Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0928Conserved hypothetical protein; Similar to PID:1050822 PID:1164975 PID:1420338 percent identity: 27.60; identified by sequence similarity; putative. (210 aa)    
Predicted Functional Partners:
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.952
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
     
 0.868
pyrF
Conserved hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.788
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
    0.786
AF_0930
Molybdenum cofactor biosynthesis protein (moeA-2); Similar to GB:L77117 SP:Q58080 PID:1591380 percent identity: 44.81; identified by sequence similarity; putative.
  
    0.622
AF_0931
Molybdenum cofactor biosynthesis protein (moeA-1); Similar to GB:L77117 SP:Q58296 PID:1591564 percent identity: 50.83; identified by sequence similarity; putative.
  
    0.622
ilvE
Branched-chain amino acid aminotransferase (ilvE); Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.604
trpS
tryptophanyl-tRNA synthetase (trpS); Similar to GB:L77117 SP:Q58810 PID:1592065 percent identity: 52.41; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.532
AF_2138
Phosphoserine phosphatase (serB); Similar to GB:L77117 PID:1592204 percent identity: 50.71; identified by sequence similarity; putative; Belongs to the HAD-like hydrolase superfamily. SerB family.
 
  
 0.516
AF_0936
Conserved hypothetical protein; Similar to GB:L77117 PID:1591577 percent identity: 29.60; identified by sequence similarity; putative.
     
 0.486
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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