close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0935Homoserine dehydrogenase (hom); Similar to GB:L77117 PID:1500499 percent identity: 47.85; identified by sequence similarity; putative. (326 aa)    
Predicted Functional Partners:
AF_0700
Aspartate kinase (lysC); Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 49.13; identified by sequence similarity; putative; Belongs to the aspartokinase family.
 
 0.993
asd
Aspartate-semialdehyde dehydrogenase (asd); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.990
ilvE
Branched-chain amino acid aminotransferase (ilvE); Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.988
dapA
Dihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.962
ilvH
Acetolactate synthase, small subunit (ilvN); Similar to GB:L77117 SP:Q57625 PID:1590918 percent identity: 60.38; identified by sequence similarity; putative; Belongs to the acetolactate synthase small subunit family.
  
  
 0.929
AF_2112
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Similar to PID:1103707 SP:P55299 percent identity: 28.08; identified by sequence similarity; putative.
  
 
 0.929
AF_1316
Threonine synthase (thrC-2); Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.917
AF_1185
Iron-sulfur cluster binding protein; Similar to GB:L77117 SP:Q57563 PID:1590877 percent identity: 36.67; identified by sequence similarity; putative.
     
  0.900
AF_1186
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57564 PID:1498865 percent identity: 56.43; identified by sequence similarity; putative.
     
 0.900
AF_0551
Threonine synthase (thrC-1); Similar to GB:L77117 PID:1592106 percent identity: 40.50; identified by sequence similarity; putative.
  
 
 0.895
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.