Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
rpiARibose 5-phosphate isomerase (rpi); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa)    
Predicted Functional Partners:
surE
surE stationary-phase survival protein (surE); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.974
AF_0861
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hps-1); Similar to GB:L77117 SP:Q58842 PID:1592092 percent identity: 30.59; identified by sequence similarity; putative.
    
 0.950
AF_0401
Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative.
 
  
 0.937
AF_0458
Phosphomannomutase (pmm); Similar to GB:L77117 PID:1591745 percent identity: 39.46; identified by sequence similarity; putative; Belongs to the phosphohexose mutase family.
    
 0.935
prs1
Ribose-phosphate pyrophosphokinase (prsA-1); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 
 0.934
prs2
Ribose-phosphate pyrophosphokinase (prsA-2); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 
 0.934
fae-hps
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hps-2); Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
    
 0.933
pdxS
Ethylene-inducible protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
    
  0.802
pdxT
Imidazoleglycerol-phosphate synthase, subunit H, putative; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
     
  0.800
AF_1341
Thymidine phosphorylase (deoA-1); Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
     
 0.777
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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