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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0972DNA polymerase III, subunit epsilon (dnaQ); Similar to GB:K00985 SP:P03007 GB:X04027 PID:1208975 PID:147679 percent identity: 31.90; identified by sequence similarity; putative. (205 aa)    
Predicted Functional Partners:
AF_0971
Conserved hypothetical protein; Similar to GP:1794166 percent identity: 25.78; identified by sequence similarity; putative.
 
  
 0.923
pcn
Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
 
 0.917
AF_0969
Proline permease (putP-2); Similar to SP:P07117 GB:L01132 GB:L01133 GB:L01150 GB:L01151 percent identity: 27.40; identified by sequence similarity; putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.867
rpl30
LSU ribosomal protein L30P (rpl30P); Similar to GB:L77117 SP:P54046 PID:1591178 percent identity: 55.92; identified by sequence similarity; putative.
  
 0.731
AF_2088
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative.
   
 
 0.674
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.646
AF_2254
ATP-dependent RNA helicase, DEAD-family (deaD); Similar to GB:L77117 SP:Q58083 PID:1591383 percent identity: 52.20; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
  
 0.646
AF_1395
Conserved hypothetical protein; Similar to GB:L77117 PID:1592047 percent identity: 45.41; identified by sequence similarity; putative; In the N-terminal section; belongs to the UPF0200 family.
     
 0.644
rpl10
LSU ribosomal protein L10E (rpl10E); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 0.613
metG
methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
  
 0.612
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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