Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0976acetyl-CoA synthetase (acs-5); Similar to GB:L17309 SP:P39062 PID:348053 PID:2293224 GB:AL009126 percent identity: 36.21; identified by sequence similarity; putative. (551 aa)    
Predicted Functional Partners:
AF_0975
acetyl-CoA synthetase (acs-4); Similar to GB:M63968 SP:P27095 PID:150032 percent identity: 42.26; identified by sequence similarity; putative.
 
   
0.833
AF_0974
Bile acid-inducible operon protein F (baiF-2); Similar to GP:1799782 percent identity: 30.03; identified by sequence similarity; putative.
 
   
 0.791
AF_0973
Bile acid-inducible operon protein F (baiF-1); Similar to GP:1799782 percent identity: 30.77; identified by sequence similarity; putative.
 
   
 0.774
AF_0969
Proline permease (putP-2); Similar to SP:P07117 GB:L01132 GB:L01133 GB:L01150 GB:L01151 percent identity: 27.40; identified by sequence similarity; putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.690
icd
Isocitrate dehydrogenase, NADP (icd); Similar to GB:J02799 SP:P08200 PID:146432 GB:U00096 PID:1651560 percent identity: 57.18; identified by sequence similarity; putative; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 
 0.663
AF_1340
Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative.
  
 
 0.655
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
  
 
 0.600
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.595
AF_1098
Fumarase (fum-1); Similar to GB:L77117 SP:Q58034 PID:1591328 percent identity: 49.13; identified by sequence similarity; putative.
  
  
 0.557
AF_0971
Conserved hypothetical protein; Similar to GP:1794166 percent identity: 25.78; identified by sequence similarity; putative.
   
 
 0.556
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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