Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0994Conserved hypothetical protein; Similar to SP:P54168 PID:1256633 GB:AL009126 percent identity: 43.75; identified by sequence similarity; putative. (185 aa)    
Predicted Functional Partners:
AF_0861
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hps-1); Similar to GB:L77117 SP:Q58842 PID:1592092 percent identity: 30.59; identified by sequence similarity; putative.
       0.624
aspS
aspartyl-tRNA synthetase (aspS); Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
       0.624
AF_2370
Conserved hypothetical protein; Similar to GB:L77117 PID:1499721 percent identity: 29.41; identified by sequence similarity; putative; Belongs to the UPF0148 family.
       0.624
radA
DNA repair protein RAD51 (radA); Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
       0.590
AF_0927
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57662 PID:1498984 percent identity: 47.83; identified by sequence similarity; putative.
       0.569
rps15
SSU ribosomal protein S15P (rps15P); Similar to GB:L77117 SP:P54012 PID:1590839 percent identity: 62.00; identified by sequence similarity; putative.
 
  
 0.510
pth
Conserved hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
       0.410
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.