Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mtaD2N-ethylammeline chlorohydrolase (trzA-2); Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (416 aa)    
Predicted Functional Partners:
AF_1788
Methylthioadenosine phosphorylase (mtaP); Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
 
 0.957
AF_0886
S-adenosylhomocysteinase hydrolase (ahcY-1); Similar to GB:L77117 PID:1592034 percent identity: 31.71; identified by sequence similarity; putative.
  
 
 0.918
ahcY
S-adenosylhomocysteinase hydrolase (ahcY-2); May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.918
speE
Spermidine synthase (speE); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.915
mtaD1
N-ethylammeline chlorohydrolase (trzA-1); Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
  
  
 
0.907
AF_0996
Type II secretion system protein (gspE-3); Similar to GB:L77117 SP:Q58310 PID:1591575 percent identity: 41.71; identified by sequence similarity; putative.
     
 0.599
AF_0995
Conserved hypothetical protein; Similar to GB:L77117 PID:1591923 percent identity: 26.90; identified by sequence similarity; putative.
       0.594
AF_0998
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57978 PID:1591264 percent identity: 27.52; identified by sequence similarity; putative.
       0.554
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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