node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AF_0115 | cobB2 | AF_0115 | AF_0112 | Conserved hypothetical protein; Similar to GB:X52543 PID:46506 SP:P55177 percent identity: 31.85; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.595 |
AF_0115 | nadE | AF_0115 | AF_1000 | Conserved hypothetical protein; Similar to GB:X52543 PID:46506 SP:P55177 percent identity: 31.85; identified by sequence similarity; putative. | NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.936 |
AF_0821 | AF_1488 | AF_0821 | AF_1488 | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | 0.930 |
AF_0821 | AF_2315 | AF_0821 | AF_2315 | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | 0.930 |
AF_0821 | cobB1 | AF_0821 | AF_1676 | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.407 |
AF_0821 | cobB2 | AF_0821 | AF_0112 | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.407 |
AF_0821 | nadC | AF_0821 | AF_1839 | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | Nicotinate-nucleotide pyrophosphorylase (nadC); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.969 |
AF_0821 | nadE | AF_0821 | AF_1000 | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.832 |
AF_0821 | nadK | AF_0821 | AF_2373 | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.417 |
AF_0999 | nadE | AF_0999 | AF_1000 | Predicted coding region AF_0999; Hypothetical protein; identified by GeneMark; putative. | NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.773 |
AF_1039 | nadE | AF_1039 | AF_1000 | Conserved hypothetical protein; Similar to GB:M20144 SP:P40403 PID:289302 GB:AL009126 percent identity: 26.56; identified by sequence similarity; putative. | NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.746 |
AF_1488 | AF_0821 | AF_1488 | AF_0821 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | 0.930 |
AF_1488 | AF_2315 | AF_1488 | AF_2315 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | 0.905 |
AF_1488 | cobB1 | AF_1488 | AF_1676 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.955 |
AF_1488 | cobB2 | AF_1488 | AF_0112 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.955 |
AF_1488 | nadC | AF_1488 | AF_1839 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Nicotinate-nucleotide pyrophosphorylase (nadC); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.923 |
AF_1488 | nadE | AF_1488 | AF_1000 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.945 |
AF_1488 | nadK | AF_1488 | AF_2373 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.916 |
AF_2315 | AF_0821 | AF_2315 | AF_0821 | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to SP:Q10641 PID:1340096 percent identity: 34.33; identified by sequence similarity; putative. | 0.930 |
AF_2315 | AF_1488 | AF_2315 | AF_1488 | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | 0.905 |