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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1002Conserved hypothetical protein; Similar to PID:1001103 PID:1001123 percent identity: 35.54; identified by sequence similarity; putative. (151 aa)    
Predicted Functional Partners:
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
       0.691
AF_1001
Predicted coding region AF_1001; Hypothetical protein; identified by GeneMark; putative.
       0.576
AF_1003
Predicted coding region AF_1003; Hypothetical protein; identified by GeneMark; putative.
       0.553
nadE
NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
       0.470
rgy
Reverse gyrase (top-RG); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
     
 0.464
AF_0378
CODH nickel-insertion accessory protein (cooC-1); Similar to GB:L77117 SP:Q58233 PID:1499647 percent identity: 35.71; identified by sequence similarity; putative.
      
 0.463
AF_1685
CODH nickel-insertion accessory protein (cooC-2); Similar to GB:L77117 SP:Q58233 PID:1499647 percent identity: 47.37; identified by sequence similarity; putative.
      
 0.463
AF_0999
Predicted coding region AF_0999; Hypothetical protein; identified by GeneMark; putative.
       0.456
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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