Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1020Predicted coding region AF_1020; Hypothetical protein; identified by GeneMark; putative. (165 aa)    
Predicted Functional Partners:
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
       0.793
AF_1017
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58207 PID:1591494 percent identity: 37.84; identified by sequence similarity; putative.
       0.678
AF_1018
ABC transporter, ATP-binding protein; Similar to GB:L77117 SP:Q58206 PID:1591493 percent identity: 57.71; identified by sequence similarity; putative.
       0.678
AF_1019
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58205 PID:1499617 percent identity: 23.74; identified by sequence similarity; putative.
       0.678
AF_2154
Conserved hypothetical protein; Similar to GB:L77117 PID:1500525 percent identity: 40.14; identified by sequence similarity; putative; Belongs to the UPF0179 family.
  
   
 0.653
AF_1021
ABC transporter, ATP-binding protein; Similar to GB:L77117 PID:1499865 percent identity: 37.82; identified by sequence similarity; putative.
 
   
 0.633
AF_1810
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57567 PID:1498868 percent identity: 43.77; identified by sequence similarity; putative.
       0.624
AF_1829
F420H2:quinone oxidoreductase, 39.7 kDa subunit, putative; Similar to SP:P15602 percent identity: 44.09; identified by sequence similarity; putative.
       0.624
AF_1830
F420H2:quinone oxidoreductase, 45 kDa subunit (nuoD); Similar to PIR:S45666 percent identity: 80.00; identified by sequence similarity; putative.
       0.624
pyrB
Aspartate carbamoyltransferase, catalytic subunit (pyrB); Similar to GB:L77117 PID:1500476 percent identity: 60.74; identified by sequence similarity; putative.
       0.618
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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