close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_10274-hydroxyphenylacetate-3-hydroxylase (hpaA-3); Similar to PID:974146 percent identity: 21.03; identified by sequence similarity; putative. (480 aa)    
Predicted Functional Partners:
AF_0885
4-hydroxyphenylacetate-3-hydroxylase (hpaA-2); Similar to PID:974146 percent identity: 26.01; identified by sequence similarity; putative.
  
  
0.916
AF_1028
3-ketoacyl-CoA thiolase (fadA-1); Similar to GP:1742272 percent identity: 38.83; identified by sequence similarity; putative.
     
 0.677
AF_1029
long-chain-fatty-acid--CoA ligase (fadD-5); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 37.94; identified by sequence similarity; putative.
       0.644
mre11
DNA repair protein RAD32 (rad32); Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
       0.421
AF_1030
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58824 PID:1592079 percent identity: 45.44; identified by sequence similarity; putative.
       0.417
rad50
Purine NTPase, putative; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
       0.417
AF_1033
Conserved hypothetical protein; Similar to SP:Q60269 PID:1522647 percent identity: 36.54; identified by sequence similarity; putative.
       0.417
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.