Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_1068Conserved hypothetical protein; Similar to GB:L77117 SP:Q57659 PID:1498981 percent identity: 50.38; identified by sequence similarity; putative. (145 aa)    
Predicted Functional Partners:
albA1
Conserved hypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family.
 
     0.805
tfe
Transcription initiation factor IIE, subunit alpha, putative; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and dest [...]
  
     0.655
rps15
SSU ribosomal protein S15P (rps15P); Similar to GB:L77117 SP:P54012 PID:1590839 percent identity: 62.00; identified by sequence similarity; putative.
       0.618
rps17e
SSU ribosomal protein S17E (rps17E); Similar to PIR:S63968 percent identity: 52.63; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS17 family.
 
     0.609
rnp4
Conserved hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
 
     0.575
AF_0504
Conserved hypothetical protein; Similar to GB:L77117 PID:1500528 percent identity: 43.59; identified by sequence similarity; putative; Belongs to the UPF0282 family.
  
   
 0.550
mer
N5,N10-methylenetetrahydromethanopterin reductase (mer-1); Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT; Belongs to the mer family.
 
     0.518
AF_2409
Iron-sulfur cluster binding protein; Similar to percent identity: 28.21; identified by sequence similarity; putative.
  
    0.512
AF_0472
Predicted coding region AF_0472; Hypothetical protein; identified by GeneMark; putative.
  
     0.509
AF_1966
Conserved hypothetical protein; Similar to GB:L77117 PID:1591643 percent identity: 28.65; identified by sequence similarity; putative.
 
     0.488
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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