Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1097Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase (manC); Similar to PID:559389 percent identity: 43.08; identified by sequence similarity; putative; Belongs to the mannose-6-phosphate isomerase type 2 family. (448 aa)    
Predicted Functional Partners:
AF_0458
Phosphomannomutase (pmm); Similar to GB:L77117 PID:1591745 percent identity: 39.46; identified by sequence similarity; putative; Belongs to the phosphohexose mutase family.
 
 
 0.980
AF_0035
Mannosephosphate isomerase, putative; Similar to GB:D16594 PID:451216 SP:Q59935 percent identity: 31.30; identified by sequence similarity; putative.
  
 
 0.946
AF_1494
Predicted coding region AF_1494; Hypothetical protein; identified by GeneMark; putative.
    
  0.925
AF_0325
Glucose-1-phosphate thymidylyltransferase (graD-2); Similar to PID:763512 percent identity: 43.11; identified by sequence similarity; putative.
  
 
 0.910
AF_0242
Glucose-1-phosphate thymidylyltransferase (graD-1); Similar to PID:763512 percent identity: 27.69; identified by sequence similarity; putative.
  
 
 0.908
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
  0.900
AF_0302
UDP-glucose dehydrogenase (ugd-1); Similar to GB:L77117 PID:1591706 percent identity: 43.83; identified by sequence similarity; putative.
  
 
 0.883
AF_0596
UDP-glucose dehydrogenase (ugd-2); Similar to GB:L77117 PID:1591706 percent identity: 44.10; identified by sequence similarity; putative.
  
 
 0.883
AF_0361
UDP-glucose 4-epimerase (galE-1); Similar to GB:L77117 SP:Q57664 PID:1590951 percent identity: 38.64; identified by sequence similarity; putative.
  
 
 0.862
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
  
 0.525
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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