Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1099Fumarase (fum-2); Similar to GB:L77117 SP:Q58690 PID:1591932 percent identity: 53.38; identified by sequence similarity; putative. (272 aa)    
Predicted Functional Partners:
AF_1098
Fumarase (fum-1); Similar to GB:L77117 SP:Q58034 PID:1591328 percent identity: 49.13; identified by sequence similarity; putative.
 0.999
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
  
 
 0.981
AF_0682
Succinate dehydrogenase, iron-sulfur subunit B (sdhB); Similar to GB:X70908 PID:396212 percent identity: 51.27; identified by sequence similarity; putative.
  
 
 0.969
AF_0683
Succinate dehydrogenase, subunit C (sdhC); Similar to GP:1524299 percent identity: 36.56; identified by sequence similarity; putative.
  
 
 0.959
sdhD
Succinate dehydrogenase, subunit D (sdhD); Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 
 0.958
AF_0681
Succinate dehydrogenase, flavoprotein subunit A (sdhA); Similar to GP:1524302 percent identity: 48.23; identified by sequence similarity; putative.
  
 
 0.953
AF_1340
Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative.
  
 
 0.944
AF_1727
Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative.
  
 
 0.941
argH
Argininosuccinate lyase (argH); Similar to SP:Q58201 PID:1591489 GB:L77117 SP:Q58201 PID:1591489 percent identity: 42.23; identified by sequence similarity; putative.
    
 0.839
AF_2129
Aspartate aminotransferase (aspB-2); Similar to PID:1146246 SP:P53001 GB:AL009126 percent identity: 45.38; identified by sequence similarity; putative.
    
 0.808
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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