Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
spt4DNA-directed RNA polymerase, subunit E'' (rpoE2); Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (62 aa)    
Predicted Functional Partners:
AF_1117
DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative.
 
 
 0.997
rps27ae
SSU ribosomal protein S27AE (rps27AE); Similar to GB:L77117 SP:P54031 PID:1591098 percent identity: 60.00; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS31 family.
 
    0.984
spt5
LSU ribosomal protein L24A (rpl24A); Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
 
 0.979
rpoP
Predicted coding region AF_0056; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
   
 
 0.961
AF_1115
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
    0.945
rps24e
SSU ribosomal protein S24E (rps24E); Similar to GB:L77117 SP:P54032 PID:1591099 percent identity: 40.20; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS24 family.
  
    0.928
rpoH
DNA-directed RNA polymerase, subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
   
 
 0.894
rpoB1
DNA-directed RNA polymerase, subunit B' (rpoB1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
   
 
 0.888
rpoL
DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
 
 
 
 0.882
rpoK
DNA-directed RNA polymerase, subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
  
 
 
 0.882
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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