Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_1118Predicted coding region AF_1118; Hypothetical protein; identified by GeneMark; putative. (178 aa)    
Predicted Functional Partners:
rps24e
SSU ribosomal protein S24E (rps24E); Similar to GB:L77117 SP:P54032 PID:1591099 percent identity: 40.20; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS24 family.
       0.590
AF_1115
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
       0.590
spt4
DNA-directed RNA polymerase, subunit E'' (rpoE2); Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
       0.590
AF_1117
DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative.
       0.590
kae1
O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
       0.571
rps27ae
SSU ribosomal protein S27AE (rps27AE); Similar to GB:L77117 SP:P54031 PID:1591098 percent identity: 60.00; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.571
AF_1119
Predicted coding region AF_1119; Hypothetical protein; identified by GeneMark; putative.
       0.540
AF_1120
Predicted coding region AF_1120; Hypothetical protein; identified by GeneMark; putative.
       0.505
AF_1121
Transcriptional regulatory protein, AsnC family; Similar to SP:P42180 percent identity: 35.79; identified by sequence similarity; putative.
       0.438
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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