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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1126P450 cytochrome, putative; Similar to PID:699154 percent identity: 30.50; identified by sequence similarity; putative. (151 aa)    
Predicted Functional Partners:
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
       0.620
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
     
 0.555
AF_1664
Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
    0.548
rpl13
LSU ribosomal protein L13P (rpl13P); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
       0.513
rps9
SSU ribosomal protein S9P (rps9P); Similar to SP:P05763 GB:M76567 PID:148778 percent identity: 59.54; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family.
       0.488
AF_1247
Conserved hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
     
 0.487
rpl18e
LSU ribosomal protein L18E (rpl18E); Similar to SP:P12733 GB:M76567 PID:148774 PID:148776 percent identity: 53.85; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL18 family.
       0.484
AF_0741
Conserved hypothetical protein; Similar to GB:L77117 PID:1591729 percent identity: 31.53; identified by sequence similarity; putative.
       0.478
rpoN
DNA-directed RNA polymerase, subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
       0.475
eif5a
Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
     
 0.424
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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