Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1149Large helicase-related protein (lhr-1); Similar to GB:L77117 SP:Q57742 PID:1591016 percent identity: 34.46; identified by sequence similarity; putative. (892 aa)    
Predicted Functional Partners:
AF_1155
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60344 PID:1498797 percent identity: 37.05; identified by sequence similarity; putative.
 
    0.868
AF_1193
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60344 PID:1498797 percent identity: 36.49; identified by sequence similarity; putative.
 
    0.798
AF_0382
Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative.
     
 0.684
AF_1148
Transcriptional regulatory protein, AsnC family; Similar to GB:L77117 SP:Q57615 PID:1498922 percent identity: 32.62; identified by sequence similarity; putative.
 
 
   0.659
lig
DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
    0.546
pfdB
erpK protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
 
     0.535
AF_1725
DNA ligase, putative; Similar to SP:P54875 GB:AE000666 PID:1279773 percent identity: 32.69; identified by sequence similarity; putative.
 
    0.508
radB
DNA repair protein REC; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity).
  
 
 0.504
AF_2361
mRNA 3'-end processing factor, putative; Similar to GP:1707412 percent identity: 30.49; identified by sequence similarity; putative.
 
    0.492
AF_0372
Conserved hypothetical protein; Similar to GB:Z35277 SP:P39756 PID:580895 PID:1648855 GB:AL009126 percent identity: 30.16; identified by sequence similarity; putative.
       0.488
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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