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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1192Conserved hypothetical protein; Similar to GB:L77117 SP:Q58010 PID:1591298 percent identity: 39.55; identified by sequence similarity; putative. (664 aa)    
Predicted Functional Partners:
AF_0932
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58010 PID:1591298 percent identity: 34.43; identified by sequence similarity; putative.
 
 
 
0.918
AF_1938
Conserved hypothetical protein; Catalyzes the reversible conversion of a variety of acids to the corresponding acyl-CoA esters. Shows the highest activity with the aryl acids, indoleacetate and phenylacetate, as compared to acetate. In the reverse direction, phenylacetyl-CoA is the best substrate. Seems to be involved primarily in the degradation of aryl-CoA esters to the corresponding acids. Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters. In the C-terminal section; belongs to the acetate CoA ligase alpha subunit family.
 
 
 
0.917
AF_1211
Conserved hypothetical protein; Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate. Can use other substrates such as propionyl-CoA and butyryl-CoA, but not phenylacetyl-CoA. Seems to be involved primarily in the conversion of acetyl-CoA to acetate. Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters; In the C-terminal section; belongs to the acetate CoA ligase beta subunit family.
 
 
 
0.748
AF_1511
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58010 PID:1591298 percent identity: 37.68; identified by sequence similarity; putative.
 
 
 
0.748
AF_1190
3-hydroxyacyl-CoA dehydrogenase (hbd-7); Similar to PID:1055222 SP:P52041 percent identity: 46.45; identified by sequence similarity; putative.
       0.687
menB
Dihydroxynaphthoic acid synthase (menB); Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
       0.672
AF_1340
Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative.
  
  
 0.637
AF_1193
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60344 PID:1498797 percent identity: 36.49; identified by sequence similarity; putative.
       0.627
AF_1194
Predicted coding region AF_1194; Hypothetical protein; identified by GeneMark; putative.
       0.618
rfcL
Activator 1, replication factor C, 53 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. Belongs to the activator 1 small subunits family. RfcL subfamily.
       0.608
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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