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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1193Conserved hypothetical protein; Similar to GB:L77117 SP:Q60344 PID:1498797 percent identity: 36.49; identified by sequence similarity; putative. (193 aa)    
Predicted Functional Partners:
rfcL
Activator 1, replication factor C, 53 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. Belongs to the activator 1 small subunits family. RfcL subfamily.
 
     0.804
AF_1194
Predicted coding region AF_1194; Hypothetical protein; identified by GeneMark; putative.
       0.786
mer-2
N5,N10-methylenetetrahydromethanopterin reductase (mer-2); Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT; Belongs to the mer family.
       0.675
AF_1149
Large helicase-related protein (lhr-1); Similar to GB:L77117 SP:Q57742 PID:1591016 percent identity: 34.46; identified by sequence similarity; putative.
 
    0.642
AF_1192
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58010 PID:1591298 percent identity: 39.55; identified by sequence similarity; putative.
       0.627
AF_2040
Conserved hypothetical protein; Similar to GB:L77117 PID:1591727 percent identity: 27.75; identified by sequence similarity; putative.
  
     0.627
dnaG
Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
     0.620
rpl21e
LSU ribosomal protein L21E (rpl21E); Similar to GB:L77117 SP:P54013 PID:1590841 percent identity: 53.19; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL21 family.
  
     0.603
AF_1531
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60345 PID:1498798 percent identity: 43.68; identified by sequence similarity; putative.
  
     0.591
AF_1977
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58006 PID:1591294 percent identity: 38.46; identified by sequence similarity; putative.
  
     0.587
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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