Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prf1Peptide chain release factor eRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (407 aa)    
Predicted Functional Partners:
AF_0004
RNase L inhibitor; Similar to GB:L77117 SP:Q58129 PID:1591435 percent identity: 54.45; identified by sequence similarity; putative.
  
 
 0.981
tuf
Translation elongation factor EF-1, subunit alpha (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 0.980
rpl15e
LSU ribosomal protein L15E (rpl15E); Similar to GB:L77117 SP:P54060 PID:1591645 percent identity: 70.31; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 0.960
rps15
SSU ribosomal protein S15P (rps15P); Similar to GB:L77117 SP:P54012 PID:1590839 percent identity: 62.00; identified by sequence similarity; putative.
 
 0.944
rpl10
LSU ribosomal protein L10E (rpl10E); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.934
rpl24
LSU ribosomal protein L24P (rpl24P); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
  0.933
rps2
SSU ribosomal protein S2P (rps2P); Similar to GB:L77117 SP:P54109 PID:1591644 percent identity: 58.33; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
  
 0.932
rps4e
SSU ribosomal protein S4E (rps4E); Similar to GB:L77117 SP:P54039 PID:1591170 percent identity: 48.92; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.927
rps12
SSU ribosomal protein S12P (rps12P); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
 
 0.926
rpl37ae
LSU ribosomal protein L37AE (rpl37AE); Binds to the 23S rRNA.
 
  0.924
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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