Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1233Conserved hypothetical protein; Similar to GP:1787271 percent identity: 28.95; identified by sequence similarity; putative. (211 aa)    
Predicted Functional Partners:
AF_1234
Mutator protein MutT (mutT); Similar to GB:L77117 PID:1500003 percent identity: 63.64; identified by sequence similarity; putative.
     
 0.825
tfs
Transcription-associated protein TFIIS; Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to ind [...]
       0.808
AF_1232
Conserved hypothetical protein; Similar to GP:1707681 percent identity: 30.90; identified by sequence similarity; putative.
 
     0.799
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
       0.724
hisB
Imidazoleglycerol-phosphate dehydrogenase/histidinol-phosphatase (hisB); Similar to GB:L77117 SP:Q58109 PID:1591413 percent identity: 42.24; identified by sequence similarity; putative.
  
  
 0.625
hisI
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (hisIE); Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.616
AF_1230
Predicted coding region AF_1230; Hypothetical protein; identified by GeneMark; putative.
       0.557
AF_1231
Predicted coding region AF_1231; Hypothetical protein; identified by GeneMark; putative.
       0.557
AF_1229
Conserved hypothetical protein; Similar to GB:L77117 PID:1592186 percent identity: 29.97; identified by sequence similarity; putative.
       0.532
AF_1223
Conserved hypothetical protein; Similar to SP:P31125 GB:U00096 PID:1787813 percent identity: 21.40; identified by sequence similarity; putative.
 
    0.501
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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