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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1234Mutator protein MutT (mutT); Similar to GB:L77117 PID:1500003 percent identity: 63.64; identified by sequence similarity; putative. (137 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase (argH); Similar to SP:Q58201 PID:1591489 GB:L77117 SP:Q58201 PID:1591489 percent identity: 42.23; identified by sequence similarity; putative.
    
 0.907
AF_1695
Thiamine biosynthesis protein (apbA); Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
      0.896
tfs
Transcription-associated protein TFIIS; Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to ind [...]
       0.847
AF_1233
Conserved hypothetical protein; Similar to GP:1787271 percent identity: 28.95; identified by sequence similarity; putative.
     
 0.834
AF_1232
Conserved hypothetical protein; Similar to GP:1707681 percent identity: 30.90; identified by sequence similarity; putative.
       0.773
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
     
 0.665
AF_2200
Mutator protein MutT, putative; Similar to GB:L77117 PID:1500003 percent identity: 41.98; identified by sequence similarity; putative.
  
  
 0.568
AF_1230
Predicted coding region AF_1230; Hypothetical protein; identified by GeneMark; putative.
       0.559
AF_1231
Predicted coding region AF_1231; Hypothetical protein; identified by GeneMark; putative.
       0.559
pyrD
Dihydroorotase dehydrogenase (pyrD); Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
  
  
 0.555
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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