Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1234Mutator protein MutT (mutT); Similar to GB:L77117 PID:1500003 percent identity: 63.64; identified by sequence similarity; putative. (137 aa)    
Predicted Functional Partners:
tfs
Transcription-associated protein TFIIS; Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to ind [...]
       0.906
argH
Argininosuccinate lyase (argH); Similar to SP:Q58201 PID:1591489 GB:L77117 SP:Q58201 PID:1591489 percent identity: 42.23; identified by sequence similarity; putative.
    
 0.905
AF_1695
Thiamine biosynthesis protein (apbA); Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
      0.895
AF_1233
Conserved hypothetical protein; Similar to GP:1787271 percent identity: 28.95; identified by sequence similarity; putative.
     
 0.825
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
     
 0.810
AF_1232
Conserved hypothetical protein; Similar to GP:1707681 percent identity: 30.90; identified by sequence similarity; putative.
       0.773
pcn
Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
     
 0.689
asd-2
Phosphatidylserine decarboxylase (psd2); Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer).
     
 0.636
AF_2046
Cytochrome oxidase, subunit I, putative; Similar to GP:1773053 percent identity: 25.14; identified by sequence similarity; putative.
       0.616
AF_2044
CDP-diacylglycerol--serine O-phosphatidyltransferase (pssA); Similar to GB:L77117 SP:Q58609 PID:1591841 percent identity: 36.65; identified by sequence similarity; putative.
       0.611
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.