| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_1117 | rpoD | AF_1117 | AF_2282 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.998 |
| AF_1117 | rpoH | AF_1117 | AF_1885 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | DNA-directed RNA polymerase, subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| AF_1117 | rpoK | AF_1117 | AF_1131 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | DNA-directed RNA polymerase, subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.999 |
| AF_1117 | rpoL | AF_1117 | AF_0207 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.994 |
| AF_1117 | rpoN | AF_1117 | AF_1130 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | DNA-directed RNA polymerase, subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.998 |
| AF_1117 | rpoP | AF_1117 | AF_0056 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | Predicted coding region AF_0056; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.999 |
| AF_1117 | tbp | AF_1117 | AF_0373 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | Transcription initiation factor IID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity). | 0.989 |
| AF_1117 | tfb | AF_1117 | AF_1299 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.447 |
| AF_1117 | tfe | AF_1117 | AF_0757 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | Transcription initiation factor IIE, subunit alpha, putative; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and dest [...] | 0.755 |
| AF_1117 | tfs | AF_1117 | AF_1235 | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | Transcription-associated protein TFIIS; Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to ind [...] | 0.952 |
| rpoD | AF_1117 | AF_2282 | AF_1117 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit E' (rpoE1); Similar to SP:Q57840 PID:1591102 GB:L77117 SP:Q57840 PID:1591102 percent identity: 48.35; identified by sequence similarity; putative. | 0.998 |
| rpoD | rpoH | AF_2282 | AF_1885 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| rpoD | rpoK | AF_2282 | AF_1131 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.999 |
| rpoD | rpoL | AF_2282 | AF_0207 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.997 |
| rpoD | rpoN | AF_2282 | AF_1130 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.999 |
| rpoD | rpoP | AF_2282 | AF_0056 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Predicted coding region AF_0056; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.999 |
| rpoD | tbp | AF_2282 | AF_0373 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription initiation factor IID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity). | 0.990 |
| rpoD | tfb | AF_2282 | AF_1299 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.993 |
| rpoD | tfe | AF_2282 | AF_0757 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription initiation factor IIE, subunit alpha, putative; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and dest [...] | 0.992 |
| rpoD | tfs | AF_2282 | AF_1235 | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription-associated protein TFIIS; Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to ind [...] | 0.947 |
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